Zuclopenthixol Decanoate Injection is used to treat mental/mood conditions (such as schizophrenia, psychosis).
 
Description:
Zuclopenthixol is a typical antipsychotic that belongs to the thioxanthene class.
It is available in different forms:
Zuclopenthixol decanoate (Clopixol Depot, Cisordinol Depot): This is a long-acting intramuscular injection given every two or three weeks to individuals with schizophrenia who struggle with medication compliance and experience frequent relapses of illness1.
Zuclopenthixol acetate (Clopixol-Acuphase, Cisordinol-Acutard): This is a shorter-acting intramuscular injection used for the acute sedation of psychotic inpatients. Its effect peaks at 48–72 hours, providing 2–3 days of sedation1.
Zuclopenthixol dihydrochloride (Clopixol, Cisordinol): This is an oral tablet used for the treatment of schizophrenia in individuals who are compliant with oral medication. It is also used in the treatment of acute bipolar mania1.
Dosing:
Zuclopenthixol decanoate (long-acting injection) comes in 200 mg and 500 mg ampoules.
The most common dosage range is 200–400 mg every 4 weeks2.
Pharmacology:
Zuclopenthixol acts as a D1 and D2 antagonist, α1-adrenergic antagonist, and 5-HT2 antagonist.
While it is approved for use in several countries, including Australia, Canada, Ireland, India, New Zealand, Singapore, South Africa, and the UK, it is not approved for use in the United States1.
Remember to consult a healthcare professional for personalized advice regarding the use of Zuclopenthixol Decanoate Injection. If you have any further questions or need additional information, feel free to ask! 😊