Papaverine is used to produce erections in some men with erectile dysfunction.
Papaverine Hydrochloride Injection is a medication used for specific purposes. Let’s explore its details:
Description:
Papaverine Hydrochloride, USP, is the hydrochloride of an alkaloid obtained from opium or prepared synthetically.
It belongs to the benzylisoquinoline group of alkaloids and does not contain a phenanthrene group like morphine and codeine.
Papaverine Hydrochloride occurs as white crystals or white crystalline powder.
It is a smooth-muscle relaxant available in vials containing 30 mg/mL for parenteral administration.
Each vial also contains edetate disodium 0.005%, and the 10 mL vials include chlorobutanol 0.5% as a preservative.
Papaverine Hydrochloride Injection is used under the direction of a physician1.
Clinical Pharmacology:
Papaverine relaxes smooth muscles, especially in larger arteries, promoting vasodilation.
It acts directly on muscle tissue, unrelated to muscle innervation.
Its antispasmodic effect is notable in the vascular system, bronchial musculature, gastrointestinal, biliary, and urinary tracts.
Minimal central nervous system effects, but large doses may cause mild sedation.
Papaverine stimulates respiration by acting on carotid and aortic body chemoreceptors1.
Indications and Usage:
Papaverine is used to produce erections in some men with erectile dysfunction.
When injected into the penis (intracavernosal), it increases blood flow, resulting in an erection2.
Remember to follow your doctor’s instructions carefully when using Papaverine Hydrochloride Injection. If you have any specific questions or need further information, feel free to ask! 😊