Nicardipine Hydrochloride Injection is used to treat high blood pressure and to control angina (chest pain). It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard.
Nicardipine hydrochloride injection is a calcium channel blocker indicated for the short-term treatment of hypertension when oral therapy is not feasible. Here are some key points about it:
Description:
Nicardipine hydrochloride injection is a calcium channel blocker.
It works by relaxing and widening the blood vessels, which helps lower blood pressure.
The medication is administered via injection under the supervision of a healthcare professional.
Common side effects include headache, hypotension (low blood pressure), tachycardia (rapid heart rate), and nausea/vomiting.
Dosage and Administration:
Individualize dosage based on the severity of hypertension and patient response.
Single-dose vials must be diluted before use.
When substituting for oral nicardipine therapy, use the intravenous infusion rate as follows:
Oral Nicardipine Dose Equivalent: IV Infusion Rate
20 mg q8h: 0.5 mg/hr
30 mg q8h: 1.2 mg/hr
40 mg q8h: 2.2 mg/hr
Adjust the infusion rate based on the desired blood pressure reduction.
Precautions:
Avoid using small veins (e.g., dorsum of the hand or wrist) to reduce the possibility of venous thrombosis, phlebitis, and vascular impairment.
Change the site of infusion every 12 hours to minimize the risk of peripheral venous irritation.
Monitor response closely in patients with angina, congestive heart failure, impaired hepatic function, portal hypertension, renal impairment, and pheochromocytoma.
Remember to consult a healthcare professional for personalized advice regarding the use of Nicardipine Hydrochloride Injection. If you have any further questions or need additional information, feel free to ask! 😊