Nefopam is most commonly used to treat pain after surgery, dental pain, muscular pain, and pain associated with cancer.
Nefopam Hydrochloride Injection is a centrally acting, non-opioid painkiller primarily used to treat moderate to severe pain. Let’s explore more about it:
Mechanism of Action:
Nefopam acts in the brain and spinal cord to relieve pain via novel mechanisms:
Antinociceptive Effects: It inhibits the reuptake of three monoamines (serotonin, norepinephrine, and dopamine), which contributes to its pain-relieving properties.
Antihyperalgesic Effects: It helps reduce heightened sensitivity to pain (hyperalgesia).
Uses:
Pain Relief: Nefopam is effective in managing pain.
It is a non-opioid alternative, making it suitable for patients who cannot tolerate opioids or need an alternative approach.
Common Side Effects:
Nausea
Dryness in mouth
Vertigo
Abdominal pain
Diarrhea
Sleepiness
Sweating
Injection site pain
Palpitations
Urinary retention
Remember, always consult your healthcare provider for personalized advice. 😊🌟