Naltrexone is a medication with interesting properties. Let’s dive into the details:
Mechanism of Action:
Naltrexone is a pure opiate antagonist, meaning it has little or no agonist activity.
Its mechanism of action in alcoholism treatment is not fully understood, but preclinical data suggest involvement of the endogenous opioid system1.
Indications:
Naltrexone is indicated for:
Alcohol Dependence: It helps reduce alcohol cravings and prevent relapse.
Opioid Blockade: It blocks the effects of exogenously administered opioids.
It is particularly useful in maintaining abstinence from alcohol and opioids.
Chemical Information:
CAS Number: 16590-41-3
Molecular Formula: C20H23NO4
Molecular Weight: 341.41 g/mol (anhydrous form)