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Famotidine for Injection

Famotidine injection is used in people who are hospitalized to treat certain conditions in which the stomach produces too much acid or to treat ulcers (sores in the lining of the stomach or intestine) that were not successfully treated with other medications.

Famotidine for Injection is a medication used for specific purposes. Let’s delve into the details:

  • Description: Famotidine is an antacid that reduces the amount of acid produced in the stomach. It is used to treat and prevent heartburn, indigestion, and other symptoms caused by excessive stomach acid. Additionally, it is employed to treat and prevent stomach ulcers, reflux disease, and certain rarer conditions1.
  • Clinical Pharmacology:
    • Famotidine is a competitive inhibitor of histamine H2-receptors.
    • Its primary pharmacologic activity is the inhibition of gastric secretion.
    • Both acid concentration and volume of gastric secretion are suppressed by famotidine.
    • Changes in pepsin secretion are proportional to volume output.
    • The onset of the antisecretory effect occurs within one hour after oral administration.
    • The maximum effect is dose-dependent and occurs within one to three hours.
    • Duration of inhibition of secretion by doses of 20 mg and 40 mg is 10 to 12 hours.
    • After intravenous administration, the maximum effect is achieved within 30 minutes.
    • Single intravenous doses of 10 mg and 20 mg inhibit nocturnal secretion for 10 to 12 hours.
    • Famotidine Injection is intended for intravenous use only2.
  • Indications and Usage:
    • Famotidine Injection is supplied as a concentrated solution for intravenous injection.
    • It is intended for intravenous use only.
    • Famotidine is used in people who are hospitalized to treat conditions where the stomach produces too much acid or to treat ulcers that were not successfully treated with other medications3.
  • Dosage and Administration:
    • For injection, 20 mg should be diluted to 5 to 10 mL with a compatible diluent and injected no faster than 10 mg/min.
    • For infusion, 20 mg should be diluted in 100 mL of dextrose 5% or another compatible diluent and infused over 15 to 30 minutes4.

Remember to consult your healthcare provider for personalized advice regarding the use of Famotidine for Injection in your specific situation. 😊

Famotidine for Injection

  • Strengths

    20 mg, 40 mg

  • Container

    Glass Vial

  • Use

    Famotidine injection is used in people who are hospitalized to treat certain conditions in which the stomach produces too much acid or to treat ulcers (sores in the lining of the stomach or intestine) that were not successfully treated with other medications.

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