Famotidine injection is used in people who are hospitalized to treat certain conditions in which the stomach produces too much acid or to treat ulcers (sores in the lining of the stomach or intestine) that were not successfully treated with other medications.
Famotidine Injection is a medication used to treat various conditions related to excess stomach acid. Let me provide you with some information about it:
Description:
Famotidine is a histamine H2-receptor antagonist.
It is a white to pale yellow crystalline compound that is freely soluble in glacial acetic acid, slightly soluble in methanol, very slightly soluble in water, and practically insoluble in ethanol.
Famotidine Injection is supplied as a sterile concentrated solution for intravenous injection.
Each mL of the single-dose solution contains 10 mg of famotidine and inactive ingredients such as L-aspartic acid, mannitol, and Water for Injection1.
Clinical Pharmacology:
Famotidine inhibits gastric secretion by being a competitive inhibitor of histamine H2-receptors.
Both the acid concentration and volume of gastric secretion are suppressed by famotidine.
The onset of the antisecretory effect occurs within one hour after oral administration.
The maximum effect is dose-dependent and occurs within one to three hours.
Duration of inhibition of secretion by doses of 20 mg and 40 mg is 10 to 12 hours.
After intravenous administration, the maximum effect is achieved within 30 minutes.
Single intravenous doses of 10 mg and 20 mg inhibit nocturnal secretion for a period of 10 to 12 hours1.
Indications and Usage:
Famotidine Injection is used to treat:
Duodenal ulcer
Zollinger-Ellison syndrome
Other conditions that cause excess stomach acid2.
Remember to consult your healthcare provider for personalized advice, and if you have further questions or need additional information, feel free to ask! 😊