Esomeprazole injection is used to treat conditions where there is too much acid in the stomach.
Esomeprazole sodium for injection is a proton pump inhibitor (PPI) used for specific purposes. Let’s explore more about it:
Indications and Usage:
Esomeprazole sodium for injection is indicated for the:
Short-term treatment of Gastroesophageal Reflux Disease (GERD) with erosive esophagitis (EE) in adults and pediatric patients aged 1 month to 17 years. It serves as an alternative to oral therapy when oral esomeprazole is not feasible or appropriate.
Risk reduction of rebleeding of gastric or duodenal ulcers following therapeutic endoscopy for acute bleeding gastric or duodenal ulcers in adults.
Dosage and Administration:
For GERD with Erosive Esophagitis:
The recommended adult dosage is either 20 mg or 40 mg once daily by intravenous injection (no less than 3 minutes) or intravenous infusion (10 minutes to 30 minutes) for up to 10 days.
The recommended pediatric dosage varies based on age and weight.
For Risk Reduction of Rebleeding of Gastric and Duodenal Ulcers:
The recommended adult dosage is 80 mg administered as an intravenous infusion over 30 minutes, followed by a continuous infusion of 8 mg/hour for a total treatment duration of 72 hours.
Dosage adjustment is necessary for patients with hepatic impairment.
Preparation and Administration:
Esomeprazole sodium for injection is available as a lyophilized powder in a single-dose vial for reconstitution.
Proper preparation and administration instructions are essential.
Contraindications:
Patients with known hypersensitivity to any component of the formulation or to substituted benzimidazoles.
Patients receiving rilpivirine-containing products.
Warnings and Precautions:
Gastric Malignancy: Symptomatic response to therapy does not exclude the presence of gastric malignancy. Consider additional follow-up and diagnostic testing.
Acute Tubulointerstitial Nephritis: Discontinue treatment and evaluate patients.
Remember to consult a healthcare professional for personalized advice regarding the use of Esomeprazole Sodium for Injection. If you have any further questions or need additional information, feel free to ask! 😊