Diatrizoate Meglumine and Diatrizoate Sodium Injection
Diatrizoate Meglumine and Diatrizoate Sodium Injection is a water-soluble, radiopaque diagnostic medium used for various imaging procedures. Let’s explore its details:
Composition:
Diatrizoate Meglumine: A triiodinated benzoic acid derivative containing 37% (w/v) organically bound iodine.
Diatrizoate Sodium: Monosodium, 3,5-diacetamido-2,4,6-triiodobenzoate.
Each mL contains 370 mg iodine and 3.68 mg (0.16 mEq) sodium.
Clinical Uses:
Excretory Urography: Enhances visualization of the urinary system.
Aortography: Imaging of the aorta.
Angiocardiography: Includes ventriculography, pulmonary angiography, and selective coronary arteriography.
Peripheral Angiography: For peripheral arteries and veins.
Intravenous Digital Arteriography: Visualizing blood vessels.
Computed Tomographic Head and Body Imaging: Enhances CT scans.
Selective Renal and Visceral Arteriography: Imaging of kidneys and visceral organs.
Central Venography: Visualizing central veins.
Renal Venography: Imaging of renal veins.
Pharmacology:
Intravascular injection opacifies vessels, allowing radiographic visualization.
Not metabolized; excreted unchanged in urine.
Plasma concentration at 10 minutes reflects dose corrected to body size.
Precautions:
Not for Intrathecal Use: Must not be given into the spine.
Liver and Kidney Disease: Use with caution.
Edetate Calcium Disodium: Added as a sequestering stabilizing agent.
Clear, Colorless to Pale Yellow Solution.
Remember to consult your healthcare provider for personalized advice regarding the use of Diatrizoate Meglumine and Diatrizoate Sodium Injection. If you have any specific questions or need further information, feel free to ask! 😊